This site is intended for healthcare professionals only


Effect of statins on COPD

Wen Zhang, Yi Zhang, Chuan-Wei Li, Paul Jones, Chen Wang & Ye Fan
Chest 2017;152(6):1159–1168
doi: 10.1016/j.chest.2017.08.015


Therapy that improves the management of chronic obstructive pulmonary disease (COPD) is urgently needed. In a meta-analysis of 10 randomised controlled trials involving 1471 patients, Wen Zhang from Xinqiao Hospital, Beijing, and his colleagues sought to determine the clinical efficacy of statin therapy in COPD. They observed that statin drugs improved exercise tolerance, pulmonary function and quality of life in patients with COPD. The authors also found that COPD patients with hyperlipidaemia, increased systemic inflammation or co-morbid cardiovascular disease (CVD) demonstrated more benefits from statin therapy than those without, and that there was no association between statin therapy and survival rates (although only a few trails in this analysis focused on that outcome). Findings support routine CVD assessment for COPD patients who have a cardiovascular indication for statin drug treatment, as it may confer benefits to the pulmonary system. They recommend running a large randomised controlled trial to test these hypotheses.

Other summaries

Media partners

Developed in partnership with

Funded by

Media partners:

The Primary Care Respiratory Academy has been developed and is produced by Cogora, the publisher of Pulse, Nursing in Practice, Healthcare Leader, Management in Practice and The Pharmacist working in partnership with PCRS.

All educational content for the website and videos has been initiated and produced by PCRS and Cogora.

The Primary Care Respiratory Academy is sponsored by Chiesi Ltd.